How to Cite
Liu, G. et al. “Synthesis and Antifungal Activities of Biquinazoline Diselenides Compounds”. Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry, vol.VOL 76, no. 586, https://raco.cat/index.php/afinidad/article/view/359064.
Abstract
A series of novel biquinazoline diselenide compounds was designed and synthesized with substituted 4-chloroquinazoline and sodium diselenide. Their structures were confirmed by IR, 1H NMR, 13CNMR, and elemental analyses. The antifungal activity of the new compounds was evaluated by growth rate method in vitro. Compound 1b, 1c, 1d, 1h, 1iand 1j were found to have activities against nine kinds of phytopathogenic fungi cell lines, G. zeae, F. oxysporum, C. mandshurica, R. solani, T. cucumeris, S. sclerotiorum, B. cinerea, P. infestans and C. gloeosporioides. Moreover, compared with the commercial antifungal drugs Hymexazol, 1b exerted better antifungal effects on corresponding bacterial lines at 50 μg/mL.