This monograph, coordinated bt Magda Polo and Tania Alba, brings together a series of five articles that, from the late Middle Ages to the present day, and taking into account different artistic languages, highlight the aforementioned importance of images and artistic practices in times of crisis. These not only bear witness to the vicissitudes, consequences and collective understanding of pandemics such as the plague, the so-called Spanish flu or the recent Covid-19, in which we are still immersed, but also fulfill an important function: protective, cathartic and even sociabilizing.