How to Cite
Abdelrazek, Fathy M.; Mohamed, Ashraf M. “Reinvestigation of the Reaction of Phenacy lMalononitrile with Hydrazines under Solvent Conditions”. Afinidad. Journal of Chemical Engineering Theoretical and Applied Chemistry, 2008, vol.VOL 65, no. 533, https://raco.cat/index.php/afinidad/article/view/281452.
Abstract
Phenacylmalononitrile 3 reacts with hydrazine hydrate in refluxing dioxan to afford the iminopyridazine derivative 6 and the pyrazolo[3,4-c]pyridazine derivative 7.Compound 3 reacts also with phenylhydrazine in refluxing ethanol to afford the iminopyridazine derivative 11 along with the phenylhydrazone derivative 12. Compound 12 could be cyclized into the pyrazolo[3,4-c]pyridazine derivative 13 upon reflux with sodium ethoxide.