Identification of Suitable Contrast Enhancement Technique for Improving the Quality of Astrocytoma Histopathological Images.

Contrast enhancement plays an important part in image processing. In histology, the application of a contrast enhancement technique is necessary since it can help pathologists in diagnosing the sample slides by increasing the visibility of the morphological and features of cells in an image. Various techniques have been proposed to enhance the contrast of microscopic images. Thus, this paper aimed to study the effectiveness of contrast enhancement techniques in enhancing the Ki67 images of astrocytoma. Three contrast enhancement techniques consist of contrast stretching, histogram equalization, and CLAHE techniques were proposed to enhance the sample images. The performance of each technique was compared by computing seven quantitative measures. The CLAHE technique was preferred for enhancing the contrast of the astrocytoma images. This technique produces good results especially in contrast enhancement, edge conservation and enhancement, brightness preservation, and minimum distortions to the enhanced images.